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After adrenaline: watch for 4 hours
Observe for at least 4 hours after the last adrenaline dose — reactions can relapse or come back. Biphasic reactions follow 3–20% of episodes, within 48 hours. Keep patients overnight if the reaction was severe or refractory, or if they live alone, are remote from care or presented late in the evening.
ASCIA Acute Management of Anaphylaxis (2026): Actions after adrenalineS
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