Uncombable hair is a real genetic diagnosis

Uncombable hair syndrome, also called spun-glass hair, gives children dry, frizzy, often fair hair that won't lie flat however much it is brushed. Under a microscope the shafts are triangular or grooved instead of round. In 2016 researchers traced it to mutations in three genes needed to build the hair shaft: PADI3, TGM3 and TCHH. Most cases are autosomal recessive, and the hair usually improves with age.